Lots of good thought going into this!
My dehumidifier installation in on the Texas Gulf Coast, and I think we're at 30ยบ latitude... I seldom see humidities below 40% inside or outside unless something really strange happens with the weather. The humidifier is actually for an indoor walk-in cigar humidor at a business in Houston.
The occasional foggy mornings that are right about room temperature outside bring in lots of humidity, and there are no A/C calls to bring it down. This is especially true at those times when people also are taking showers. In general, I don't care all that much about the precise humidity, and since I'm going by the LED's on a dimmer switch, I don't really have that precise of an insight on the actual humidity unless I look at the thermostat, but since I was writing the programming, I just copied and changed as I went and incorporated the entire comfort range in 1% increments since it's available from the dimmer. My dehumidifier isn't tremendously oversized, and it will take a long time to bring the humidity back into range when it is called, so I'm not worried about driving it batty. I'm sure that before it gets the humidity down, the A/C will be called to keep the temperature in check, and the humidity will drop anyway.
I still think we deserve to tune it so that we don't get chapped lips/hands, but don't grow mold in the showers either, nor should we feel sticky or overly warm at a certain temperature just because of the heat index. We will also be able to 'kick it down' if we do have showers going or are boiling something in the kitchen or mopping or whatever adds humidity to the house - just so we can stay 'ahead' of the gain in humidity.
It's purely for comfort. I've never seen excessive humidity or dryness in this house since we've lived here except during Harvey, but we've previously manipulated it with the cooling system as much as possible before installing the dehumidifier last week. In fact, I have a scene that turns on the A/C, drops the set temperature, and turns the fan to "always on" when you press one of the 8-way buttons in the master bath. If I'm going to take a shower (and my wife is putting on makeup), you just press the button and the house cools and removes excess humidity. I still have to figure out how to reverse that progress with the programming.