I am using an IP blocklist on my edge router. When the list is active and I am using my Android phone at home over WIFI, UD mobile does not connect properly. Before trashing my IP blocklist, can you provide an IP whitelist I might try? 

Any sub domain at isy.io so *.isy.io

It is very likley there is another issue, please got to Settings > Systems > Your system.  Press Test Remote Connection, then post a screenshot of the error message.  Be sure there is no personal info shown in the screen shot.

If you get an error saying your are on a local connection, then expand local connection settings then press the Test Local Connection button, then post a screenshot of any errors.

Test is successful but the individual status indicators are missing: I can still query the device and control the device from that panel but status icon is still missing or unresponsive. This condition is true for WIFI and cell phone connection

I can work around it by disabling two of my blocklists: debl (fail2ban IP blocklist) and doh (public DoH-Provider)

actually whitelisting isy.io resolved the problem